Autophagy. Volume 4 : Cancer, other pathologies, inflammation, immunity, infection, and aging için kapak resmi
Başlık:
Autophagy. Volume 4 : Cancer, other pathologies, inflammation, immunity, infection, and aging
Dil:
English
ISBN:
9780124055339
Yayın Bilgileri:
San Diego, California :

Academic Press,

2014.

©2014
Fiziksel Tanımlama:
1 online resource (315 pages)

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E-Kitap 1343992-1001 QH603 .L9 .A986 2014 eb Elsevier E-Kitap Koleksiyonu
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Özet

Özet

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection and Aging, Volume 4 - Mitophagy presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson's Disease, cardiac aging, and skeletal muscle atrophy. The most current understanding of the proteins and pathways involved in mitophagy are covered, with specific attention to Nix and Bnip3, PINK1/Parkin, Atg32, and FUNDC1. The role of mitophagy in cancer, neurodegeneration, aging, infection, and inflammation is also discussed providing essential insights into the pathogenesis of a variety of mitochondria dysfunction-related diseases.

This book is an asset to newcomers as a concise overview of the current knowledge on mitophagy, while serving as an excellent update reference for more experienced scientists working on other aspects of autophagy. From these well-developed foundations, researchers, translational scientists, and practitioners may work to better implement more effective therapies against some of the most devastating human diseases.

Volumes in the Series